Imatinib has a fatal impact on morphology, pairing stability and survival of adult Schistosoma mansoni in vitro

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

Brian Druker, Moshe Talpaz, Debra Resta et al. · New England Journal of Medicine · 2001 · 5.2K citations · Full text

Medicine, Oncology, Pharmacology +12

The molecular biology of chronic myeloid leukemia

Michael W. Deininger, John M. Goldman, Junia V. Melo · Blood · 2000 · 1.6K citations

Medicine, Molecular Biology, Oncology +14

The genome of the blood fluke Schistosoma mansoni

Matthew Berriman, Brian J. Haas, Philip T. LoVerde et al. · Nature · 2009 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571).

Bhushan Nagar, William G. Bornmann, Patricia Pellicena et al. · PubMed · 2002 · 941 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study

Richard A. Larson, Brian Druker, François Guilhot et al. · Blood · 2008 · 637 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +6