Protection against DSP-4-induced neurotoxicity by deprenyl is not related to its inhibition of MAO B

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

Kan Chiba, Anthony J. Trevor, Neal Castagnoli · Biochemical and Biophysical Research Communications · 1984 · 1.1K citations

Biochemistry, Medicine, Neurotransmitter +12

Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

Richard E. Heikkila, Lawrence Manzino, Felicitas S. Cabbat et al. · Nature · 1984 · 1K citations

Psychoactive Drug, Monoamine Oxidase Inhibitors, Dopaminergic Neurotoxicity +8

Effect of Deprenyl on the Progression of Disability in Early Parkinson's Disease

New England Journal of Medicine · 1989 · 916 citations

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

Sanford P. Markey, Jan N. Johannessen, Chuang C. Chiueh et al. · Nature · 1984 · 779 citations

Psychoactive Drug, Neurophysiology, Medicine +10

The Effect of Deprenyl (Selegiline) on the Natural History of Parkinson's Disease

James W. Tetrud, J. William Langston · Science · 1989 · 645 citations

Monoamine Oxidase B, Psychiatry, Medicine +15