Concepedia

Cytotoxicity of anthracyclines: Correlation with cellular uptake, intracellular distribution and DNA binding

Frank Gieseler, Harald Biersack, T. Brieden, J. Manderscheid, V. Nüßler

Annals of Hematology · 1994 · 34 citations · 12 references

DOI

Concepts

References

12

In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions

Rob Pieters, AH Loonen, DR Huismans et al. · Blood · 1990 · 231 citations · Full text

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DNA topoisomerase II as the primary target of anti-tumor anthracyclines.

Franco Zunino, Giovanni Capranico · PubMed · 1990 · 161 citations

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Sequence-selective topoisomerase II inhibition by anthracycline derivatives in SV40 DNA: relationship with DNA binding affinity and cytotoxicity

Giovanni Capranico, Franco Zunino, Kurt W. Kohn et al. · Biochemistry · 1990 · 156 citations

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Anthracyclines and their C-13 alcohol metabolites: growth inhibition and DNA damage following incubation with human tumor cells in culture

Mary J. Kuffel, Joel M. Reid, Matthew M. Ames · Cancer Chemotherapy and Pharmacology · 1992 · 115 citations

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Kinetics of daunorubicin transport by P‐glycoprotein of intact cancer cells

Ellen C. Spoelstra, Hans V. Westerhoff, Henk Dekker et al. · European Journal of Biochemistry · 1992 · 105 citations · Full text

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