In vitro kinetics of styrene and styrene oxide metabolism in rat, mouse, and human

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.

F. Peter Guengerich, M V Martin, Philippe Beaune et al. · Journal of Biological Chemistry · 1986 · 730 citations · Full text

Medicine, Biochemistry, Pharmacology +17

A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans

J.C. Ramsey, Melvin E. Andersen · Toxicology and Applied Pharmacology · 1984 · 677 citations

Pharmacy, Pharmacokinetics, Toxicology +10

A rapid and simple procedure for chronic cannulation of the rat jugular vein.

P.G. Harms, Sergio R. Ojeda · Journal of Applied Physiology · 1974 · 638 citations

Medicine, Surgery, Vascular Surgery +4

A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide

Franz Oesch, D. M. JERINA, Jeanette M. Daly · Biochimica et Biophysica Acta (BBA) - Enzymology · 1971 · 415 citations

Life Sciences, Biochemistry, Pharmacology +7

Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450

Ronald Boecker, F. Peter Guengerich · Journal of Medicinal Chemistry · 1986 · 323 citations · Full text

Medicine, Biochemistry, Pharmacology +13