Concepedia

TNF-α Induces Two Distinct Caspase-8 Activation Pathways

Lai Wang, Fenghe Du, Xiaodong Wang

Cell · 2008 · 1.4K citations · 38 references

DOI

Concepts

References

38

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 6K citations · Full text

Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

Chunying Du, Min Fang, Yucheng Li et al. · Cell · 2000 · 3.5K citations · Full text

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NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

Cun-Yu Wang, Marty W. Mayo, Robert G. Korneluk et al. · Science · 1998 · 2.7K citations · Full text

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Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes

Olivier Micheau, Jürg Tschopp · Cell · 2003 · 2.7K citations · Full text

, , +12

Inhibition of death receptor signals by cellular FLIP

Martin Irmler, Margot Thome, Michael Hahne et al. · Nature · 1997 · 2.6K citations · Full text

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