Concepedia

Tibolone Metabolism in Human Liver Is Catalyzed by 3α/3β-Hydroxysteroid Dehydrogenase Activities of the Four Isoforms of the Aldo-Keto Reductase (AKR)1C Subfamily

Stephan Steckelbroeck, Busola Oyesanmi, Seon Hwa Lee, Helenius J. Kloosterboer, T.M. Penning

Journal of Pharmacology and Experimental Therapeutics · 2006 · 67 citations · 36 references

DOI

Concepts

References

36

Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1‒AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

T.M. Penning, Michael E. Burczynski, Joseph M. Jez et al. · Biochemical Journal · 2000 · 572 citations · Full text

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Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1–AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

T.M. Penning, Michael E. Burczynski, Joseph M. Jez et al. · Biochemical Journal · 2000 · 350 citations

, , +17

Human Cytosolic 3α-Hydroxysteroid Dehydrogenases of the Aldo-keto Reductase Superfamily Display Significant 3β-Hydroxysteroid Dehydrogenase Activity

Stephan Steckelbroeck, Sridhar Gopishetty, Busola Oyesanmi et al. · Journal of Biological Chemistry · 2004 · 273 citations · Full text

, , +17

Molecular Endocrinology of Hydroxysteroid Dehydrogenases

T.M. Penning · Endocrine Reviews · 1997 · 230 citations

, , +14

Expression Cloning and Characterization of Oxidative 17β- and 3α-Hydroxysteroid Dehydrogenases from Rat and Human Prostate

Michael G. Biswas, David W. Russell · Journal of Biological Chemistry · 1997 · 224 citations · Full text

, , +17