Stephan Steckelbroeck

Human Cytosolic 3α-Hydroxysteroid Dehydrogenases of the Aldo-keto Reductase Superfamily Display Significant 3β-Hydroxysteroid Dehydrogenase Activity

Stephan Steckelbroeck, Yi Jin, Sridhar Gopishetty et al. · Journal of Biological Chemistry · 2004 · 270 citations · Full text

An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies

Michael C. Byrns, Stephan Steckelbroeck, T.M. Penning · Biochemical Pharmacology · 2007 · 136 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Prostaglandin F Synthase +12

Human Type 3 3α-Hydroxysteroid Dehydrogenase (Aldo-Keto Reductase 1C2) and Androgen Metabolism in Prostate Cells

Tea Lanišnik Rižner, Hsueh Kung Lin, Donna M. Peehl et al. · Endocrinology · 2003 · 130 citations · Full text

Aldo-keto Reductase, Normal Prostate, Prostate Cells +20

Aldo-keto reductase (AKR) 1C3: Role in prostate disease and the development of specific inhibitors

T.M. Penning, Stephan Steckelbroeck, David R. Bauman et al. · Molecular and Cellular Endocrinology · 2006 · 122 citations

Specific Inhibitors, Urology, Prostate Disease +5

Identification of the Major Oxidative 3α-Hydroxysteroid Dehydrogenase in Human Prostate That Converts 5α-Androstane-3α,17β-diol to 5α-Dihydrotestosterone: A Potential Therapeutic Target for Androgen-Dependent Disease

David R. Bauman, Stephan Steckelbroeck, Michelle V. Williams et al. · Molecular Endocrinology · 2005 · 118 citations · Full text

Potential Therapeutic Target, Androgen-dependent Disease, Androgen Receptor +13