In vitro selection of self-cleaving DNAs

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

Louis C. Bock, Linda C. Griffin, John Latham et al. · Nature · 1992 · 2.4K citations

Biochemistry, Natural Sciences, Hematology +7

The RNA world

W Gilbert · Nature · 1986 · 1.9K citations

Functional Genomics, Genetics, Rna Structure Prediction +6

A DNA enzyme that cleaves RNA

Ronald R. Breaker, Gerald F. Joyce · Chemistry & Biology · 1994 · 1.4K citations

Dna Enzyme, Natural Sciences, Genetics +10

Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA

Debra L. Robertson, Gerald F. Joyce · Nature · 1990 · 1.3K citations

Nucleic Acid Chemistry, Natural Sciences, Genetics +9

A DNA Aptamer That Binds Adenosine and ATP

David Huizenga, Jack W. Szostak · Biochemistry · 1995 · 1.3K citations