Concepedia

Discovery and structure–activity relationships of novel sulfonamides as potent PTP1B inhibitors

Christopher P. Holmes, Xianfeng Li, Yijun Pan, Caiding Xu, Ashok Bhandari, Claire M. Moody, Joy A. Miguel, Steven W. Ferla, M. Nuria De Francisco, Brian Frederick,

Bioorganic & Medicinal Chemistry Letters · 2005 · 35 citations · 34 references

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Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

Lori D. Klaman, Olivier Boss, Odile D. Peroni et al. · Molecular and Cellular Biology · 2000 · 1.2K citations

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Protein tyrosine phosphatases in signal transduction

Benjamin G. Neel, N. K. Tonks · Current Opinion in Cell Biology · 1997 · 763 citations

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Molecular Basis for the Dephosphorylation of the Activation Segment of the Insulin Receptor by Protein Tyrosine Phosphatase 1B

Annette Salmeen, Jannik N. Andersen, Michael P. Myers et al. · Molecular Cell · 2000 · 464 citations · Full text

, , +17

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice

Bradley A. Zinker, Cristina M. Rondinone, James M. Trevillyan et al. · Proceedings of the National Academy of Sciences · 2002 · 416 citations

, , +17

Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: A paradigm for inhibitor design

Yoram A. Puius, Yu Zhao, Michael Sullivan et al. · Proceedings of the National Academy of Sciences · 1997 · 402 citations

, , +17