Concepedia

The prognostic role of the epithelial–mesenchymal transition markers E‐cadherin and Slug in laryngeal squamous cell carcinoma

Rocco Cappellesso, Gino Marioni, Marika Crescenzi, Luciano Giacomelli, Vincenza Guzzardo, Alessio Mussato, Alberto Staffieri, Alessandro Martini, Stella Blandamura, Ambrogio Fassina

Histopathology · 2015 · 81 citations · 16 references

DOI

Abstract

EMT increases tumour recurrence risk and shortens DFS in LSCC. E-cadherin and Slug immunohistochemical analysis could be useful for identifying patients requiring more aggressive treatment after surgery.

References

16

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

Sendurai A. Mani, Wenjun Guo, Mai-Jing Liao et al. · Cell · 2008 · 8.6K citations · Full text

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Up-regulation of <i>miR-200</i> and <i>let-7</i> by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells

Yiwei Li, Timothy VandenBoom, Dejuan Kong et al. · Cancer Research · 2009 · 656 citations · Full text

MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms

Y-N Liu, JuanJuan Yin, Wassim Abou‐Kheir et al. · Oncogene · 2012 · 292 citations · Full text

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miR-200bc/429 cluster targets PLCγ1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer

Stefan Uhlmann, Jianing Zhang, Anja Schwäger et al. · Oncogene · 2010 · 200 citations

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Epithelial–mesenchymal transition in malignant mesothelioma

Ambrogio Fassina, Rocco Cappellesso, Vincenza Guzzardo et al. · Modern Pathology · 2011 · 151 citations · Full text