Aziridine biotransformation by microsomes and lethality to hepatocytes isolated from rat

Methods in Enzymology , Vol

S P Colowick, M D Joshi, Jagannathan et al. · 1966 · 26.2K citations

Biosynthesis, Engineering, Cellular Enzymology +5

[4] Isolation and use of liver cells

Peter Moldéus, Johan Högberg, Sten Orrenius · Methods in enzymology on CD-ROM/Methods in enzymology · 1978 · 1.2K citations

Hepatology, Liver Physiology, Liver Cells +5

A scheme for the colorimetric determination of microgram amounts of thiols

B. Saville · The Analyst · 1958 · 750 citations

Humanities, Gas Chromatography, Medicine +11

O-phthalaldehyde: fluorogenic detection of primary amines in the picomole range. Comparison with fluorescamine and ninhydrin.

John R. Benson, P. E. Hare · Proceedings of the National Academy of Sciences · 1975 · 737 citations · Full text

Bioorganic Chemistry, Amino Acids, Engineering +16

The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+.

Matthew D. Moore, Hjördis Thor, Gregory Moore et al. · Journal of Biological Chemistry · 1985 · 411 citations · Full text

Ca2+ Homeostasis, Cell Death, Cytosolic Ca2+ +22