Internal Medicine · 2011 · 14 citations · 10 references
MedicineInternal MedicineNephrologyHistopathologyImmunopathologyPulmonologyAutoimmune VasculitisInflammatory Disease PathologyInflammatory LesionsInterstitial NephritisTemporal Artery DiseaseVascular PathologyAntineutrophil AntibodiesAntineutrophil Cytoplasmic AntibodiesImmune-mediated VasculitisKidney Biopsy FindingsSystemic VasculitisTemporal ArteritisTemporal Artery BiopsyVascular Involvement
An 81-year-old man was hospitalized because of fever and pain in the temporal region. Temporal artery biopsy revealed temporal arteritis; steroid therapy was started. Chest computed tomography and kidney biopsy revealed interstitial pneumonia and necrotizing crescentic glomerulonephritis, respectively. Because his myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) level was 215.0 U/mL, a diagnosis of microscopic polyangitis (MPA) was made. The patient was discharged after reduction of the steroid dose. However, his respiratory symptoms exacerbated, necessitating rehospitalization. He died 1 week later due to respiratory failure. MPA rarely involves the temporal artery. In the cases of large vessel lesions, ruling out MPA is important.
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M. Gayraud, L Guillevin, Philippe Le Toumelin et al. · Arthritis & Rheumatism · 2001 · 537 citations
Temporal artery biopsy: A diagnostic tool for systemic necrotizing vasculitis
Olivier Lortholary, U. Michon-Pasturel, T. Ponge et al. · Arthritis & Rheumatism · 1999 · 135 citations
Microscopic polyangiitis (microscopic polyarteritis).
J. Charles Jennette, D. B. Thomas, Ronald J. Falk · PubMed · 2001 · 128 citations