Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling

Osamu Yamaguchi, Yoshiharu Higuchi, Shinichi Hirotani, +16

Proceedings of the National Academy of Sciences

Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

Osamu Yamaguchi, Tetsuya Watanabe, Kazuhiko Nishida, +18

Journal of Clinical Investigation

Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

Osamu Yamaguchi, Tetsuya Watanabe, Kazuhiko Nishida, +18

Journal of Clinical Investigation

Functional Analysis of Human P5, a Protein Disulfide Isomerase Homologue

M Kikuchi, E. Doi, Ikuko Tsujimoto, +2

The Journal of Biochemistry

Protein SecretionProtein FunctionBiochemistryProtein FoldingHuman P5 +10

The Antioxidant Edaravone Attenuates Pressure Overload–Induced Left Ventricular Hypertrophy

Ikuko Tsujimoto, Shungo Hikoso, Osamu Yamaguchi, +10

Hypertension

Cardiovascular ToxicityHypertensionHeart FailureCardiovascular DiseaseMedicine +13

CaMKII activates ASK1 and NF-κB to induce cardiomyocyte hypertrophy

Kazunori Kashiwase, Yoshiharu Higuchi, Shinichi Hirotani, +12

Biochemical and Biophysical Research Communications

Cardiac MuscleCardiomyopathyMolecular PhysiologySignal TransductionPhysiology +6

Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively

Kensaku Shojima, Akira Sato, Hideaki Hanaki, +8

Scientific Reports

Apicobasal secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by distinct mechanisms

Hideki Yamamoto, Chihiro Awada, Hideaki Hanaki, +5

Journal of Cell Science

Distinct MechanismsApical SecretionGlycobiologyGlycosylation ProcessingCellular Physiology +19

A Fibronectin-Independent Mechanism of Collagen Fibrillogenesis in Adult Liver Remodeling

Kei Moriya, Eunnyung Bae, Kazuhisa Honda, +7

Gastroenterology

FibrosisDevelopmental BiologyHepatologyLiver PhysiologyPathology +9

Apoptosis Signal-Regulating Kinase 1/p38 Signaling Pathway Negatively Regulates Physiological Hypertrophy

Masayuki Taniike, Osamu Yamaguchi, Ikuko Tsujimoto, +12

Circulation