Synthesis of [11C]SSR149415 and preliminary imaging studies using positron emission tomography

Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V _1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders

Guy Griebel, Jacques Simiand, Claudine Serradeil‐Le Gal et al. · Proceedings of the National Academy of Sciences · 2002 · 462 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Rhodium‐Catalyzed Asymmetric Addition of Aryl‐ and Alkenylboronic Acids to Isatins

Ryo Shintani, Mitsunori Inoue, Tamio Hayashi · Angewandte Chemie International Edition · 2006 · 321 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Immunohistochemical Localization of the Vasopressin V1b Receptor in the Rat Brain and Pituitary Gland: Anatomical Support for Its Involvement in the Central Effects of Vasopressin*

Fernando Hernando, Oscar Schoots, Stephen J. Lolait et al. · Endocrinology · 2001 · 263 citations · Full text

Medicine, Neurobiology, Neuroscience +16

Characterization of (2 S,4 R)-1-[5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1 H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a Selective and Orally Active Vasopressin V1b Receptor Antagonist

Claudine Serradeil‐Le Gal, Jean Wagnon, Jacques Simiand et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 210 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Synthesis of Novel Enantiopure Biphenyl <i>P</i>,<i>N-</i>Ligands and Application in Palladium-Catalyzed Asymmetric Addition of Arylboronic Acids to <i>N-</i>Benzylisatin

Hongshan Lai, Zhiyan Huang, Qiong Wu et al. · The Journal of Organic Chemistry · 2008 · 120 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8