Protection of pancreatic β-cells against glucotoxicity by short-term treatment with GLP-1

β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

Alexandra E. Butler, Juliette Janson, Susan Bonner‐Weir et al. · Diabetes · 2003 · 4K citations

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Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1

David A. Guertin, Deanna M. Stevens, Carson C. Thoreen et al. · Developmental Cell · 2006 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV.

Timothy J. Kieffer, Christopher H.S. McIntosh, Raymond A. Pederson · Endocrinology · 1995 · 1.1K citations

Life Sciences, Biochemistry, Endocrinology +17

Pancreatitis, Pancreatic, and Thyroid Cancer With Glucagon-Like Peptide-1–Based Therapies

Michael Elashoff, Aleksey V. Matveyenko, Belinda Gier et al. · Gastroenterology · 2011 · 931 citations · Full text

Medicine, Endocrinology, Oncology +14

Antidiabetogenic Effect of Glucagon-like Peptide-1 (7–36)amide in Normal Subjects and Patients with Diabetes Mellitus

M. Gutniak, Jens J. Holst, Bo Åhrén et al. · New England Journal of Medicine · 1992 · 875 citations · Full text

Medicine, Endocrinology, Pharmacology +17