S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein

A Cytoplasmic Protein Stimulates Normal N- <i>ras</i> p21 GTPase, But Does Not Affect Oncogenic Mutants

Meg Trahey, Frank McCormick · Science · 1987 · 1.2K citations

Life Sciences, Biochemistry, Cell Biology +13

In yeast, RAS proteins are controlling elements of adenylate cyclase

Takashi Toda, Isao Uno, Tatsuo Ishikawa et al. · Cell · 1985 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +12

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

Jeffrey Field, Jun‐ichi Nikawa, Daniel Broek et al. · Molecular and Cellular Biology · 1988 · 961 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Cloning of bovine GAP and its interaction with oncogenic ras p21

Ursula Vogel, Richard A. F. Dixon, Michael D. Schaber et al. · Nature · 1988 · 665 citations

Medicine, Genetics, Molecular Biology +12

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

Irving S. Sigal, Martin Poe, Edward M. Scolnick · Proceedings of the National Academy of Sciences · 1984 · 616 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14