Irving S. Sigal

Active human immunodeficiency virus protease is required for viral infectivity.

Nancy E. Kohl, Emilio A. Emini, William A. Schleif et al. · Proceedings of the National Academy of Sciences · 1988 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin

Richard A. F. Dixon, Brian K. Kobilka, David J. Strader et al. · Nature · 1986 · 1.3K citations

Life Sciences, Biochemistry, Pharmacology +8

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

Manuel A. Navia, Paula M.D. Fitzgerald, Brian M. McKeever et al. · Nature · 1989 · 893 citations

Life Sciences, Biochemistry, Molecular Biology +16

cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

Brian K. Kobilka, Richard A. F. Dixon, Thomas Frielle et al. · Proceedings of the National Academy of Sciences · 1987 · 683 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

Cloning of bovine GAP and its interaction with oncogenic ras p21

Ursula Vogel, Richard A. F. Dixon, Michael D. Schaber et al. · Nature · 1988 · 665 citations

Medicine, Genetics, Molecular Biology +12