Electrostatics in the Ribosomal Tunnel Modulate Chain Elongation Rates

The codon adaptation index-a measure of directional synonymous codon usage bias, and its potential applications

Paul M. Sharp, Wen‐Hsiung Li · Nucleic Acids Research · 1987 · 4.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

A "Silent" Polymorphism in the <i>MDR</i> 1 Gene Changes Substrate Specificity

Chava Kimchi‐Sarfaty, Jung Mi Oh, In‐Wha Kim et al. · Science · 2006 · 2.5K citations · Full text

Medicine, Genetics, Molecular Genetics +15

Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: A proposal for a synonymous codon choice that is optimal for the E. coli translational system

Toshimichi Ikemura · Journal of Molecular Biology · 1981 · 1.5K citations

Life Sciences, Microbiology, Molecular Biology +17

A Thermodynamic Scale for the Helix-Forming Tendencies of the Commonly Occurring Amino Acids

Karyn T. O’Neil, William F. DeGrado · Science · 1990 · 1.2K citations

Life Sciences, Biochemistry, Biophysics +17

Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes.

Peter Walter, Günter Blobel · The Journal of Cell Biology · 1981 · 815 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15