The effect of 6-methylthiohexyl isothiocyanate isolated from Wasabia japonica (wasabi) on 4-(methylnitrosamino)-1-(3-pyridyl)-1-buatnone-induced lung tumorigenesis in mice

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.

Yuesheng Zhang, Paul Talalay, C G Cho et al. · Proceedings of the National Academy of Sciences · 1992 · 1.7K citations

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Activation of <i>ras</i> Oncogenes Preceding the Onset of Neoplasia

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O6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung.

Lisa A. Peterson, Stephen S. Hecht · PubMed · 1991 · 180 citations

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Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice

Zuyu Guo, Theresa J. Smith, Erjia Wang et al. · Carcinogenesis · 1993 · 122 citations

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Vinyl carbamate epoxide, a major strong electrophilic, mutagenic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate (urethane)

Kwang-Kyun Park, Amy Liem, Bradley C. Stewart et al. · Carcinogenesis · 1993 · 112 citations

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