Klf4 Organizes Long-Range Chromosomal Interactions with the Oct4 Locus in Reprogramming and Pluripotency

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

Kazutoshi Takahashi, Shinya Yamanaka · Cell · 2006 · 26.2K citations · Full text

Tissue Engineering, Regenerative Medicine, Defined Factors +14

Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

Junying Yu, Maxim A. Vodyanik, Kim Smuga-Otto et al. · Science · 2007 · 10.2K citations

Tissue Engineering, Adult Stem Cell, Transplantation Medicine +18

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

Erez Lieberman-Aiden, Nynke L. van Berkum, Louise Williams et al. · Science · 2009 · 9.3K citations · Full text

Structural Bioinformatics, Genetics, Genomic Mechanism +21

Topological domains in mammalian genomes identified by analysis of chromatin interactions

Jesse R. Dixon, Siddarth Selvaraj, Feng Yue et al. · Nature · 2012 · 7.2K citations · Full text

Chromatin, Functional Genomics, Chromatin Structure +15

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte, David A. Orlando, Denes Hnisz et al. · Cell · 2013 · 4.2K citations · Full text

Transcriptional Regulation, Developmental Biology, Cell Regulation +9