Stereoselective total synthesis of the cytotoxic lactone (−)-spicigerolide

Direct synthesis of Z-unsaturated esters. A useful modification of the horner-emmons olefination.

W. Clark Still, Cesare Gennari · Tetrahedron Letters · 1983 · 1K citations

Natural Sciences, Chemistry, Organic Chemistry +2

Syntheses of Discodermolides Useful for Investigating Microtubule Binding and Stabilization

Deborah T. Hung, Jennie B. Nerenberg, Stuart L. Schreiber · Journal of the American Chemical Society · 1996 · 142 citations

Life Sciences, Immunology, Medicinal Chemistry +12

Application of molecular mechanics in the total stereochemical elucidation of spicigerolide, a cytotoxic 6-tetraacetyloxyheptenyl-5,6-dihydro-α-pyrone from Hyptis spicigera

Rogelio Pereda‐Miranda, Mabel Fragoso‐Serrano, Carlos M. Cerda‐García‐Rojas · Tetrahedron · 2001 · 89 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7

Structure and Stereochemistry of Pectinolides A-C, Novel Antimicrobial and Cytotoxic 5,6-Dihydro-α-pyrones from Hyptis pectinata

Rogelio Pereda‐Miranda, Lourdes Hernández, Manuela Judith Villavicencio et al. · Journal of Natural Products · 1993 · 88 citations

Pharmacy, Biochemistry, Pharmacology +9

New compounds from . X-ray crystal and molecular structures of anamarine

Anna Alemany, Cecilio Márquez, C. Pascual et al. · Tetrahedron Letters · 1979 · 54 citations

Natural Sciences, Chemistry, Medicinal Chemistry +16