A soybean Kunitz trypsin inhibitor suppresses ovarian cancer cell invasion by blocking urokinase upregulation

A rapid in vitro assay for quantitating the invasive potential of tumor cells.

Adriana Albini, Yukihide Iwamoto, Kleinman Hk et al. · PubMed · 1987 · 1.8K citations

Medicine, Cell Biology, Oncology +16

Protease Inhibitors as Cancer Chemopreventive Agents

A. C. Upton, Walter Troll, Ann R. Kennedy · Radiation Research · 1994 · 99 citations

Medicine, Oncology, Pharmacology +12

Suppression of Urokinase Expression and Invasiveness by Urinary Trypsin Inhibitor Is Mediated through Inhibition of Protein Kinase C- and MEK/ERK/c-Jun-dependent Signaling Pathways

Hiroshi Kobayashi, Mika Suzuki, Yoshiko Tanaka et al. · Journal of Biological Chemistry · 2001 · 70 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +16

Possible Adverse Effects of Soybean Anticarcinogens

Irvin E. Liener · Journal of Nutrition · 1995 · 68 citations

Pharmacy, Toxicology, Food Toxicology +13

Transforming Growth Factor-β1 Produced by Ovarian Cancer Cell Line HRA Stimulates Attachment and Invasion through an Up-regulation of Plasminogen Activator Inhibitor Type-1 in Human Peritoneal Mesothelial Cells

Yasuyuki Hirashima, Hiroshi Kobayashi, Mika Suzuki et al. · Journal of Biological Chemistry · 2003 · 64 citations · Full text

Medicine, Cell Biology, Oncology +17