Dioxin Exposure Is an Environmental Risk Factor for Ischemic Heart Disease

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

Andrew Plump, Jonathan D. Smith, Tony Hayek et al. · Cell · 1992 · 2.3K citations

Life Sciences, Genetics, Molecular Genetics +10

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

Sunny H. Zhang, Robert L. Reddick, Jorge A. Piedrahita et al. · Science · 1992 · 2.2K citations

Life Sciences, Cardiology, Genetics +17

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells.

Jorge A. Piedrahita, S H Zhang, John R. Hagaman et al. · Proceedings of the National Academy of Sciences · 1992 · 926 citations

Life Sciences, Genetics, Molecular Genetics +10

Cancer Mortality in Workers Exposed to 2,3,7,8-Tetrachlorodibenzo-P-Dioxin

Marilyn A. Fingerhut, William Halperin, David Marlow et al. · New England Journal of Medicine · 1991 · 537 citations · Full text

Pharmacy, Oncology, Toxicology +14

p27Kip1 induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells

Siva K. Kolluri, Andrew Koff, Martin Göttlicher · Genes & Development · 1999 · 376 citations · Full text

Medicine, Cancer Biology, Oncology +17