Concepedia

Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer

Óscar Aguilera, Mario F. Fraga, Esteban Ballestar, Maria F. Paz, M. Herranz, Jesús Espada, Alberto Múñoz, Manel Esteller, José Manuel González‐Sancho

Oncogene · 2006 · 339 citations · 21 references

DOI

Concepts

References

21

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

Mario F. Fraga, Esteban Ballestar, Ana Villar‐Garea et al. · Nature Genetics · 2005 · 1.9K citations

, , +13

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

Hiromu Suzuki, D. Neil Watkins, Kam-Wing Jair et al. · Nature Genetics · 2004 · 1.1K citations

, , +17

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins

Bingyu Mao, Wei Wu, Yan Li et al. · Nature · 2001 · 1K citations

, , +5

Kremen proteins are Dickkopf receptors that regulate Wnt/β-catenin signalling

Bingyu Mao, Wei Wu, Gary Davidson et al. · Nature · 2002 · 1K citations

, , +12

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

Daniel Pinto, Alex Gregorieff, Harry Begthel et al. · Genes & Development · 2003 · 1K citations · Full text

, , +17