Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Michael J. Caterina, Mark Schumacher, Makoto Tominaga et al. · Nature · 1997 · 9K citations · Full text

Acute Pain, Pain Medicine, Anesthetic Mechanism +16

The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

Makoto Tominaga, Michael J. Caterina, Annika B. Malmberg et al. · Neuron · 1998 · 3.1K citations · Full text

Health Sciences, Pain Medicine, Medicine +9

Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions

Sima Lev, Herman Moreno, Ronny Martínez et al. · Nature · 1995 · 1.4K citations

Signal Transduction, Molecular Physiology, Ion Channel +11

Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase

Jun Xing, David D. Ginty, Michael E. Greenberg · Science · 1996 · 1.3K citations

Creb Kinase, Gene Activation, Signaling Pathway +16

CREB: A Major Mediator of Neuronal Neurotrophin Responses

Steven Finkbeiner, Sohail F. Tavazoie, Anna Maloratsky et al. · Neuron · 1997 · 962 citations · Full text

Major Mediator, Neurotransmission, Neurology +5