Leukotriene B4 Levels in Human Atherosclerotic Plaques and Abdominal Aortic Aneurysms

Pleunie van den Borne, Sander W. van der Laan, Sandra M. Bovens, Dave Koole, Mark C. Kowala, Laura F. Michael, Arjan H. Schoneveld, Sander M. van de Weg, Evelyn Velema, Jean-Paul de Vries,

PLoS ONE · 2014 · 16 citations · 22 references

DOIFull text

Open access

Abstract

LTB4 levels were not associated with a vulnerable plaque phenotype or inflammatory AAA or clinical presentation. This study does not provide supportive evidence for a role of LTB4 in atherosclerotic plaque destabilization or AAA expansion. However, these data should be interpreted with care, since LTB4 measurements were performed without prior lipid extractions.

References

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