Concepedia

Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia

Anna M. Eiring, Brent D. G. Page, Ira L. Kraft, Clinton C. Mason, Nadeem A. Vellore, Diana Resetca, Matthew S. Zabriskie, T Y Zhang, Jamshid S. Khorashad, Amy Engar,

Leukemia · 2014 · 133 citations · 49 references

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49

Five-Year Follow-up of Patients Receiving Imatinib for Chronic Myeloid Leukemia

Brian Druker, François Guilhot, Stephen G. O’Brien et al. · New England Journal of Medicine · 2006 · 3.5K citations · Full text

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Stat3 as an Oncogene

Jacqueline Bromberg, Melissa H Wrzeszczynska, Geeta Devgan et al. · Cell · 1999 · 2.8K citations · Full text

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AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance

Thomas O’Hare, William C. Shakespeare, Xiaotian Zhu et al. · Cancer Cell · 2009 · 1.2K citations · Full text

, , +9

Stattic: A Small-Molecule Inhibitor of STAT3 Activation and Dimerization

Jochen Schust, Bianca Sperl, Angela Hollis et al. · Chemistry & Biology · 2006 · 1.1K citations

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Somatic <i>STAT3</i> Mutations in Large Granular Lymphocytic Leukemia

Hanna Koskela, Samuli Eldfors, Pekka Ellonen et al. · New England Journal of Medicine · 2012 · 766 citations · Full text

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