SITES OF FORMATION OF PLASMA PHOSPHOPROTEIN AND PHOSPHOLIPID IN THE ESTROGENIZED COCKEREL

Abstract

Estrogen increased plasma Ca, but not plasma total protein, phosphoprotein P, or phospholipid P, in functionally hepatectomized cockerels. Estrogen increased all four plasma constituents in sham-operated cockerels. Functional hepatectomy of the estrogenized cockerel abolished incorporation into plasma phosphoprotein of injected orthophosphate labelled with P 32 , and reduced but did not abolish incorporation of P 32 into plasma phospholipid. These observations are submitted as direct evidence that plasma phosphoprotein in the estrogenized cockerel is exclusively hepatic in origin.