Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

Honglin Li, Hong Zhu, Chi-jie Xu et al. · Cell · 1998 · 4.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

Masato Enari, Hideki Sakahira, Hideki Yokoyama et al. · Nature · 1998 · 3.2K citations

Life Sciences, Cell Biology, Molecular Biology +12

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

Amer A. Beg, David Baltimore · Science · 1996 · 3.1K citations

Life Sciences, Cell Biology, Immunology +17

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

Marta Muzio, Arul M. Chinnaiyan, Frank Kischkel et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Two CD95 (APO‐1/Fas) signaling pathways

Carsten Scaffidi · The EMBO Journal · 1998 · 3K citations · Full text

Life Sciences, Cell Biology, Immunology +12