Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus‐prone NZB × NZW mice

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Dennis M. Klinman, Ae‐Kyung Yi, Serge L. Beaucage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations · Full text

Innate Immune System, Bacteriology, Immunology +18

Controlled trial of pulse methylprednisolone versus two regimens of pulse cyclophosphamide in severe lupus nephritis

Dimitrios T. Boumpas, H A Austin, James E. Balow et al. · The Lancet · 1992 · 825 citations

Glomerulonephritis, Autoimmune Disease, Systemic Lupus Erythematosus +11

PATHOGENESIS OF THE GLOMERULONEPHRITIS OF NZB/W MICE

Paul‐Henri Lambert, Frank J. Dixon · The Journal of Experimental Medicine · 1968 · 619 citations · Full text

Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs

Arthur Μ. Krieg, Tong Wu, Risini D. Weeratna et al. · Proceedings of the National Academy of Sciences · 1998 · 399 citations · Full text

Stimulatory Cpg Motifs, Immunology, Molecular Biology +16

In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon.

Chaim O. Jacob, Peter H. van der Meide, Hugh O. McDevitt · The Journal of Experimental Medicine · 1987 · 390 citations · Full text

Immunology, Pathology, Immunotherapy +18