Sonogashira cross-coupling reaction in 4-chloro-2-trichloromethylquinazoline series is possible despite a side dimerization reaction

A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines

Kenkichi Sonogashira, Yasuo Tohda, Nobue Hagihara · Tetrahedron Letters · 1975 · 5.1K citations

Natural Sciences, Chemistry, Catalysis +11

Nanocrystalline copper(II) oxide catalyzed aza-Michael reaction and insertion of α-diazo compounds into N–H bonds of amines

M. Lakshmi Kantam, Soumi Laha, Jagjit S. Yadav et al. · Tetrahedron Letters · 2009 · 260 citations

Natural Sciences, Chemical Engineering, Chemistry +15

Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines

Pierre Verhaeghe, Nadine Azas, M. Gasquet et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 161 citations

Pharmacy, Chemistry, Medicinal Chemistry +7

A Guide to Sonogashira Cross-Coupling Reactions: The Influence of Substituents in Aryl Bromides, Acetylenes, and Phosphines

Marc Schilz, Herbert Plenio · The Journal of Organic Chemistry · 2012 · 141 citations

Natural Sciences, Chemistry, Catalysis +15

Synthesis and cytotoxicity evaluation of some benzimidazole-4,7-diones as bioreductive anticancer agents

Armand Gellis, Hervé Kovacic, Narimène Boufatah et al. · European Journal of Medicinal Chemistry · 2008 · 117 citations

Medicine, Medicinal Chemistry, Pharmacology +12