Concepedia

Mild and Highly Efficient Method for the Synthesis of 2-Arylbenzimidazoles and 2-Arylbenzothiazoles

Kiumars Bahrami, Mohammad Mehdi Khodaei, Fardin Naali

The Journal of Organic Chemistry · 2008 · 449 citations · 34 references

DOI

Concepts

Abstract

A new, convenient method for the syntheses of 2-substituted benzimidazole and benzothizole is described. Short reaction times, large-scale synthesis, easy and quick isolation of the products, excellent chemoselectivity, and excellent yields are the main advantages of this procedure.

References

34

Green oxidation with aqueous hydrogen peroxide

Ryōji Noyori, Masayo Aoki, Kazuhiko Sato · Chemical Communications · 2003 · 1.1K citations

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Green Oxidation with Aqueous Hydrogen Peroxide

Kazuhiko Sato · TRENDS IN THE SCIENCES · 2009 · 798 citations · Full text

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Synthesis and Biological Activity of Novel Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase. 2-Aryl-Substituted Benzimidazoles

Thomas Roth, Marshall Morningstar, Paul L. Boyer et al. · Journal of Medicinal Chemistry · 1997 · 370 citations · Full text

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Antitumor Benzothiazoles. 14. Synthesis and in Vitro Biological Properties of Fluorinated 2-(4-Aminophenyl)benzothiazoles

Ian Hutchinson, Mei‐Sze Chua, Helen Browne et al. · Journal of Medicinal Chemistry · 2001 · 353 citations

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Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of minimal DNA-intercalating agents which may not act via topoisomerase II

William A. Denny, Gordon W. Rewcastle, Bruce C. Baguley · Journal of Medicinal Chemistry · 1990 · 309 citations

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