Inhibition and breaking of advanced glycation end-products (AGEs) with bis-2-aminoimidazole derivatives

Standards of Medical Care in Diabetes—2014

Diabetes Care · 2013 · 4.6K citations · Full text

Medicine, Health Policy, Internal Medicine +12

The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses

Ann Marie Schmidt, Shi Du Yan, Shi Fang Yan et al. · Journal of Clinical Investigation · 2001 · 1K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

N ε-(Carboxymethyl)Lysine Adducts of Proteins Are Ligands for Receptor for Advanced Glycation End Products That Activate Cell Signaling Pathways and Modulate Gene Expression

Thomas Kislinger, Caifeng Fu, Birgit Huber et al. · Journal of Biological Chemistry · 1999 · 864 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

Rashid Deane, Itender Singh, Abhay P. Sagare et al. · Journal of Clinical Investigation · 2012 · 612 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Prevention of Diabetic Vascular Dysfunction by Guanidines: Inhibition of Nitric Oxide Synthase Versus Advanced Glycation End-Product Formation

Ronald G. Tilton, Katherine Chang, Khalid S. Hasan et al. · Diabetes · 1993 · 288 citations

Medicine, Endocrinology, Pharmacology +11