Interleukin 1 receptor antagonist reduces lethality and intestinal toxicity of 5-fluorouracil in a mouse mucositis model

Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor

Charles Hannum, Carol Wilcox, William P. Arend et al. · Nature · 1990 · 1.1K citations

Life Sciences, Immunology, Pharmacology +14

Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality.

Catherine L. Farrell, J. V. Bready, Karen Rex et al. · PubMed · 1998 · 362 citations

Medicine, Oncology, Radiation Oncology +17

Characterisation of mucosal changes in the alimentary tract following administration of irinotecan: implications for the pathobiology of mucositis

Richard M. Logan, Rachel J. Gibson, Joanne M. Bowen et al. · Cancer Chemotherapy and Pharmacology · 2007 · 187 citations

Life Sciences, Pathobiology, Pharmacology +14

Irinotecan causes severe small intestinal damage, as well as colonic damage, in the rat with implanted breast cancer

Rachel J. Gibson, Joanne M. Bowen, MARK RB INGLIS et al. · Journal of Gastroenterology and Hepatology · 2003 · 180 citations

Medicine, Oncology, Pharmacology +13

Prevention of chemotherapy-induced ulcerative mucositis by transforming growth factor beta 3.

Stephen T. Sonis, Loryn E. Lindquist, A. Van Vugt et al. · PubMed · 1994 · 148 citations

Dentistry, Oncology, Oral Biology +17