Concepedia

Characterisation of mucosal changes in the alimentary tract following administration of irinotecan: implications for the pathobiology of mucositis

Richard M. Logan, Rachel J. Gibson, Joanne M. Bowen, Andrea M. Stringer, Stephen T. Sonis, Dorothy Keefe

Cancer Chemotherapy and Pharmacology · 2007 · 187 citations · 18 references

DOI

Concepts

References

18

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.

Lalitha Iyer, Christopher D. King, P. F. Whitington et al. · Journal of Clinical Investigation · 1998 · 680 citations · Full text

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The burdens of cancer therapy

Linda S. Elting, Catherine D. Cooksley, Mark S. Chambers et al. · Cancer · 2003 · 615 citations · Full text

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Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease.

Maryla Krajewska, Hong‐Gang Wang, Stanisław Krajewski et al. · PubMed · 1997 · 435 citations

, , +10

Chemotherapy for cancer causes apoptosis that precedes hypoplasia in crypts of the small intestine in humans

Dorothy Keefe · Gut · 2000 · 366 citations · Full text

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Mucositis: Its Occurrence, Consequences, and Treatment in the Oncology Setting

José‐Luis Pico, Andrés Avila‐Garavito, Philippe Naccache · The Oncologist · 1998 · 294 citations · Full text

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