Glyburide Inhibits Dipyridamole‐induced Forearm Vasodilation but not Adenosine‐induced Forearm Vasodilation

Abstract

Opening of vascular K(ATP) channels is involved in the forearm vasodilator response to dipyridamole but not to adenosine. Differences in stimulated cell type (endothelium for adenosine versus smooth muscle cells for dipyridamole) may underlie this divergent pharmacologic profile.