A Bifunctional <i>Cinchona</i> Alkaloid‐Squaramide Catalyst for the Highly Enantioselective Conjugate Addition of Thiols to <i>trans</i>‐Chalcones

Abstract

Abstract A chiral squaramide catalysts‐promoted asymmetric sulfa‐Michael conjugated addition of thiols to trans ‐chalcones is presented. Moderate to excellent yields and high enantioselectivities (up to 99% ee ) were achieved under mild conditions.