Mechanism for the Catalytic Activation of Ecteinascidin 743 and Its Subsequent Alkylation of Guanine N2

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTMechanism for the Catalytic Activation of Ecteinascidin 743 and Its Subsequent Alkylation of Guanine N2Bob M. Moore, Frederick C. Seaman, Richard T. Wheelhouse, and Laurence H. HurleyView Author Information Drug Dynamics Institute, College of Pharmacy The University of Texas at Austin Austin, Texas 78712-1074 Cite this: J. Am. Chem. Soc. 1998, 120, 10, 2490–2491Publication Date (Web):March 3, 1998Publication History Received3 December 1997Published online3 March 1998Published inissue 1 March 1998https://pubs.acs.org/doi/10.1021/ja974109rhttps://doi.org/10.1021/ja974109rrapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views522Altmetric-Citations57LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Adducts,Alcohols,Genetics,Post-translational modification,Reaction mechanisms Get e-Alerts