Proteinpolysaccharides from human articular and costal cartilage.

Abstract

From bovine nasal cartilage two products were isolated, each consisting mainly of chondroitin sul- fate and protein (1). These were called protein- polysaccharides (PP), and the two kinds were distinguished as PP-H and PP-L. Human costal cartilage also yielded two products which, in the extraction and fractionation procedures, behaved rather like the two products from bovine nasal cartilage and were also called PP-H and PP-L (2), although they differed from the corresponding products from bovine cartilage in yield and composition. Isolation and fractionation of the prod- ucts from human cartilage was far more difficult and gave results more variable than with bovine cartilage.