Fluorescence measurements of free Ca2+ concentration in human erythrocytes using the Ca2+-indicator fura-2

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Calcium gradients in single smooth muscle cells revealed by the digital imaging microscope using Fura-2

David A. Williams, Kevin E. Fogarty, Roger Y. Tsien et al. · Nature · 1985 · 660 citations

Life Sciences, Biophysics, Cell Biology +16

Complexation in analytical chemistry

C. Furlani · Journal of Chromatography A · 1964 · 657 citations

Natural Sciences, Chemistry, Analytical Chemistry +8

Measurement of cytosolic free Ca2+ in individual small cells using fluorescence microscopy with dual excitation wavelengths

Roger Y. Tsien, T J Rink, Martin Poenie · Cell Calcium · 1985 · 655 citations

Natural Sciences, Biophysics, Cell Biology +17

Changes of free calcium levels with stages of the cell division cycle

Martin Poenie, Janet M. Alderton, Roger Y. Tsien et al. · Nature · 1985 · 591 citations

Life Sciences, Biochemistry, Cell Biology +14