Concepedia

A2B receptors mediate the induction of early genes and inhibition of arterial smooth muscle cell proliferation via Epac

P. Mayer, Annette Viktoria Hinze, Anja Harst, Ivar von Kügelgen

Cardiovascular Research · 2010 · 30 citations · 36 references

DOI

Abstract

In summary, our results demonstrate the operation of adenosine A₂(B) receptors mediating an early induction of NR4A1 and a decrease in cell proliferation via the cAMP/Epac pathway in HCASMCs.

References

36

Receptors for Purines and Pyrimidines

Geoffrey Burnstock, Alexei Verkhratsky · 2012 · 4K citations

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K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

Hiroshi Kase, Kazuyuki Iwahashi, Satoshi Nakanishi et al. · Biochemical and Biophysical Research Communications · 1987 · 942 citations

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cAMP Analog Mapping of Epac1 and cAMP Kinase

Anne Elisabeth Christensen, Frode Selheim, Johan de Rooij et al. · Journal of Biological Chemistry · 2003 · 399 citations · Full text

The A2B adenosine receptor protects against inflammation and excessive vascular adhesion

Dan Yang · Journal of Clinical Investigation · 2006 · 341 citations · Full text

NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism

Liming Pei, Hironori Waki, Bhavapriya Vaitheesvaran et al. · Nature Medicine · 2006 · 321 citations

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