Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells - Concepedia

Concepedia

Publication | Open Access

Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells

DOI Full Paper Access

82

Citations

38

References

2014

Year

Xiangning Meng, Xiuying Qi, Huanhuan Guo, Mengdi Cai, Chunxiang Li, Jing Zhu, Feng Chen, Huan Guo, Jie Li, Yuzhen Zhao,

Journal of Medical Genetics

Abstract

We demonstrate a novel specific role for NHEJ in the formation of DMs, but not HSRs, in MTX-resistant cells, and that NHEJ may be targeted for the treatment of MTX-resistant colon cancer.

References

	Year	Citations

Page 1