Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors

Expression of a multidrug-resistance gene in human tumors and tissues.

Antonio Tito Fojo, Kazumitsu Ueda, Dennis J. Slamon et al. · Proceedings of the National Academy of Sciences · 1987 · 1.6K citations · Full text

Medicine, Oncology, Pharmacology +11

DNA Topoisomerase I—Targeted Chemotherapy of Human Colon Cancer in Xenografts

Beppino C. Giovanella, John S. Stehlin, Monroe E. Wall et al. · Science · 1989 · 647 citations

Medicine, Oncology, Pharmacology +15

Isolation and genetic characterization of human KB cell lines resistant to multiple drugs

Shin‐ichi Akiyama, Antonio Tito Fojo, John A. Hanover et al. · Somatic Cell and Molecular Genetics · 1985 · 553 citations

Medicine, Genetics, Oncology +12

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

William D. Kingsbury, Jeffrey C. Boehm, Dalia R. Jakas et al. · Journal of Medicinal Chemistry · 1991 · 516 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood.

Helen S. L. Chan, Paul S. Thorner, George Haddad et al. · Journal of Clinical Oncology · 1990 · 454 citations

Medicine, Oncology, Pharmacology +17