Simulation of complex transport of nanoparticles around a tumor using tumor-microenvironment-on-chip

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Medicine, Oncology, Pharmacology +12

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

Horacio Cabral, Yu Matsumoto, Kazue Mizuno et al. · Nature Nanotechnology · 2011 · 2.4K citations

Pharmacy, Oncology, Pharmacokinetics +14

Thermodynamic analysis of the permeability of biological membranes to non-electrolytes

O. Kedem, A. Katchalsky · Biochimica et Biophysica Acta · 1958 · 2.2K citations

Natural Sciences, Biochemistry, Biophysics +14

Targeted drug delivery to tumors: Myths, reality and possibility

You Han Bae, Kinam Park · Journal of Controlled Release · 2011 · 1.9K citations · Full text

Pharmacy, Oncology, Pharmacology +12

Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size.

Marc Dellian, Dai Fukumura, Michael Leunig et al. · PubMed · 1995 · 1.7K citations

Medicine, Cancer Biology, Oncology +17