Concepedia

Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin

Matthias Elsner, B. Guldbakke, Markus Tiedge, Rex Munday, Sigurd Lenzen

Diabetologia · 2000 · 367 citations · 28 references

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28

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi · Analytical Biochemistry · 1987 · 46.9K citations

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Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

Hiroshi Yamamoto, Yasuko Uchigata, Hiroshi Okamoto · Nature · 1981 · 529 citations

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Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin

Volker Burkart, Zhao‐Qi Wang, Jürgen Radons et al. · Nature Medicine · 1999 · 373 citations

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Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells

Markus Tiedge, S Lortz, J. Drinkgern et al. · Diabetes · 1997 · 299 citations

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Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

Andrew A. Pieper, Daniel J. Brat, David K. Krug et al. · Proceedings of the National Academy of Sciences · 1999 · 297 citations

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