Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin

Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis

Marcel Leist, Barbara Single, Anna Federica Castoldi et al. · The Journal of Experimental Medicine · 1997 · 1.9K citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

Yutaka Eguchi, S Shimizu, Yoshihide Tsujimoto · PubMed · 1997 · 1.3K citations

Life Sciences, Biochemistry, Cell Biology +16

Nitric Oxide Activation of Poly(ADP-Ribose) Synthetase in Neurotoxicity

Jie Zhang, Valina L. Dawson, Ted M. Dawson et al. · Science · 1994 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +16

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

Josiane Ménissier de Murcia, C. Niedergang, Carlotta Trucco et al. · Proceedings of the National Academy of Sciences · 1997 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

Mikael J. L. Eliasson, Kenji Sampei, Allen S. Mandir et al. · Nature Medicine · 1997 · 1K citations

Life Sciences, Molecular Biology, Neuroscience +14