Journal of Asian Natural Products Research · 2014 · 29 citations · 8 references
Life SciencesBiochemistryMedicinal ChemistryMycologyPlant BiochemistryStructure-activity RelationshipsBioactive Natural ProductsFungal BiochemistryFungal Secondary MetabolitesMedicinal PlantsStructure-activity Relationship AnalysisAntioxidant Activity AssaysBioactive ConstituentsBioactive Fungal MetabolitesBioactive Plant CompoundsBioactivity ScreeningFungal Bioactive CompoundsNatural Antifungal CompoundsPharmacological Screening
Eight bibenzyl derivatives, namely dendrocandins J-Q (1-8), were isolated from the stems of Dendrobium candidum. Their structures were elucidated by 1D and 2D NMR experiments and mass spectrometry. Compounds 1-8 were examined for antioxidant activity by 1,1-diphenyl-2-picrylhydrazyl free radical scavenging assay, and the IC50 values were 36.8, 70.2, 45.0, 60.5, 87.6, 50.4, 22.3, and 30.3 μM, respectively.
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