Alterations in p53, BRCA1, ATM, PIK3CA, and HER2 genes and their effect in modifying clinicopathological characteristics and overall survival of Bulgarian patients with breast cancer

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

Medicine, Genetics, Oncology +14

High Frequency of Mutations of the <i>PIK3CA</i> Gene in Human Cancers

Yardena Samuels, Zhenghe Wang, Alberto Bardelli et al. · Science · 2004 · 3.4K citations

Medicine, Genetics, Oncology +11

Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

Deborah Ford, Douglas F. Easton, Michael R. Stratton et al. · The American Journal of Human Genetics · 1998 · 3K citations · Full text

Life Sciences, Genetics, Oncology +17

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

Jiřina Bártková, Zuzana Hořejšı́, Karen Koed et al. · Nature · 2005 · 2.7K citations

Medicine, Cancer Biology, Oncology +16

Promoter Hypermethylation and BRCA1 Inactivation in Sporadic Breast and Ovarian Tumors

Manel Esteller · JNCI Journal of the National Cancer Institute · 2000 · 1.2K citations · Full text

Medicine, Genetics, Oncology +16