Epigenetic and genetic analysis of WNT signaling pathway in sporadic colorectal cancer patients from Iran

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek et al. · Science · 1997 · 3.9K citations

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Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.

Manel Esteller, Andrew B. Sparks, Minoru Toyota et al. · PubMed · 2000 · 525 citations

Medicine, Genetics, Oncology +17

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling

Ratnam S. Seelan, Ken Taniguchi, Kausilia K. Krishnadath et al. · Nature Genetics · 2000 · 504 citations

Medicine, Genetics, Oncology +16

Aberrant Methylation of<i>APC, MGMT, RASSF2A</i>, and<i>Wif-1</i>Genes in Plasma as a Biomarker for Early Detection of Colorectal Cancer

Bo Bin Lee, Eun Ju Lee, Eun Hyun Jung et al. · Clinical Cancer Research · 2009 · 268 citations

Medicine, Genetics, Oncology +17

Hypermethylation of the APC (adenomatous Polyposis Coli) gene promoter region in human colorectal carcinoma

Mikko Hiltunen, Leena Alhonen, Jari Koıstınaho et al. · International Journal of Cancer · 1997 · 192 citations

Medicine, Genetics, Molecular Genetics +17