Microstructure for efficient continuous flow mixing

Abstract

This paper presents a micromixer for the laminar flow regime based on the principle of flow lamination. The structure is made up from a glass/silicon/glass sandwich, has a total internal volume of ≡600 nL and measures 5 mm × 10 mm. Flow rates between 1–200 µL min–1 have successfully been used. Fluorescence quenching experiments were carried out for quantification and showed 95% mixing within 15 ms.